Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.45 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787553 | 0.89 | PHLPP2 (0.61) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL23787693 | 0.87 | PHLPP2 (0.52) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL23787591 | 0.86 | PHLPP2 (0.51) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL23787791 | 0.86 | PHLPP2 (0.51) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL23787739 | 0.86 | ENPP2 (0.61) | PHLPP2ENPP2MEN1KMT2ACA2 | |
| SCHEMBL23787589 | 0.86 | ENPP2 (0.49) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL8904069 | 0.83 | PHLPP2 (0.56) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL8958917 | 0.83 | PHLPP2 (0.56) | PHLPP2ENPP2MEN1KMT2AHTT | |
| SCHEMBL13631321 | 0.82 | ENPP2 (0.54) | PHLPP2ENPP2MEN1KMT2ACA2 | |
| SCHEMBL14493323 | 0.82 | PHLPP2 (0.58) | PHLPP2ENPP2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | ACIBADEM MEHMET ALI AYDINLAR UNIVERSITESI (TR) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210275548-A1 | NOVEL DNA POLYMERASE GAMMA INHIBITOR AND USES THEREOF | POLG, POLB, POLA1 | PHLPP2 1195/4885ENPP2 2691/4885MEN1 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.