Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.32 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788330 | 0.90 | LTB4R (0.32) | HTR1ASLC6A4CYP2B6TENT4ATENT4B | |
| SCHEMBL23788591 | 0.87 | LTB4R (0.31) | CYP2B6TENT4ATENT4B | |
| SCHEMBL23788629 | 0.83 | LTB4R (0.32) | — | |
| SCHEMBL23788559 | 0.81 | — | — | |
| SCHEMBL23788424 | 0.80 | CNR2 (0.32) | — | |
| SCHEMBL23788471 | 0.80 | KDM4E (0.31) | KDM4E | |
| SCHEMBL23788321 | 0.78 | SRD5A1 (0.38) | — | |
| SCHEMBL23788557 | 0.77 | — | — | |
| SCHEMBL23788643 | 0.77 | IRAK4 (0.31) | — | |
| SCHEMBL23788536 | 0.77 | LTB4R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720857-B1 | 2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B | GALAPAGOS NV (BE) | 2021-09-08 | — | — | EP | disclosed |