Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.30 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788322 | 0.91 | GPR84 (0.35) | — | |
| SCHEMBL23788608 | 0.89 | MEN1 (0.35) | — | |
| SCHEMBL23788637 | 0.89 | IRAK4 (0.31) | — | |
| SCHEMBL23788634 | 0.87 | CYP2B6 (0.32) | CYP2B6TENT4ATENT4B | |
| SCHEMBL23788304 | 0.87 | CYP2B6 (0.32) | CYP2B6TENT4ATENT4B | |
| SCHEMBL23788627 | 0.86 | TSHR (0.33) | — | |
| SCHEMBL23788626 | 0.85 | IRAK4 (0.37) | — | |
| SCHEMBL23788620 | 0.84 | CYP2B6 (0.30) | CYP2B6TENT4ATENT4B | |
| SCHEMBL23788455 | 0.82 | PPARG (0.31) | — | |
| SCHEMBL23788552 | 0.82 | PPARG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720857-B1 | 2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B | GALAPAGOS NV (BE) | 2021-09-08 | — | — | EP | disclosed |