Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 13/20 | 0.67 |
| ▸ | CDK1 | P06493 | 12/20 | 0.67 |
| ▸ | CCND1 | P24385 | 11/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.67 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.67 |
| ▸ | CDK9 | P50750 | 11/20 | 0.66 |
| ▸ | CDK2 | P24941 | 10/20 | 0.66 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.66 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.66 |
| ▸ | GSK3A | P49840 | 4/20 | 0.66 |
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.66 |
| ▸ | CDK7 | P50613 | 3/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.66 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.66 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.66 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.66 |
| ▸ | CCND3 | P30281 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788859 | 1.00 | CDK4 (0.67) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788481 | 0.88 | CDK9 (0.70) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788860 | 0.88 | CDK9 (0.63) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788867 | 0.88 | CDK9 (0.70) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788695 | 0.88 | CDK9 (0.63) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788518 | 0.86 | CDK4 (0.60) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL23788806 | 0.86 | CDK4 (0.60) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL666139 | 0.85 | CDK4 (0.65) | CDK4CDK1CCND1CCNB1CCNB2 | |
| Hydrochloric Acid SCHEMBL665647 | 0.84 | CDK4 (0.66) | CDK4CDK1CCND1CCNB1CCNB2 | |
| SCHEMBL21473114 | 0.83 | CDK4 (0.76) | CDK4CDK1CCND1CCNB1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277037-A1 | DEUTERATED ALVOCIDIB AND ALVOCIDIB PRODRUGS | SUMITOMO PHARMA ONCOLOGY, INC. | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277037-A1 | DEUTERATED ALVOCIDIB AND ALVOCIDIB PRODRUGS | CDK4, CDK11B, CDK3 | CDK4 1/4885CDK1 4/4885CCND1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.