Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23793384 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23793391 | 0.80 | KDM4E (0.36) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23782959 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL29740958 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL25168149 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23792824 | 0.71 | KDM4E (0.36) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23782736 | 0.71 | KDM4E (0.36) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23793075 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EHPGDAPOBEC3GMAPK1 | |
| SCHEMBL23782836 | 0.65 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL23793537 | 0.65 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KDM4ENPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178780-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | ESCAPE Bio, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |