⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894945 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL18044118 | 0.78 | — | — | |
| SCHEMBL9717845 | 0.77 | — | — | |
| SCHEMBL5984891 | 0.77 | — | — | |
| SCHEMBL17607381 | 0.74 | — | — | |
| SCHEMBL17607519 | 0.73 | — | — | |
| SCHEMBL19155761 | 0.73 | RIPK1 (0.39) | — | |
| SCHEMBL17607398 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL27805437 | 0.71 | — | — | |
| SCHEMBL25838861 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976085-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | Aperion Synthesis S.A. (PL) | 2024-05-07 | — | — | US | disclosed |
| US-20240076308-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2024-03-07 | — | — | US | disclosed |
| CN-112236421-B | Pyrazole derivatives and pest control agents | 组合化学工业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| EP-4196267-B1 | NOVEL RUTHENIUM COMPLEXES, METHODS OF THEIR PREPARATION AND APPLICATION THEREOF IN OLEFIN CROSS METATHESIS | APEIRON SYNTHESIS SA (PL) | 2023-11-29 | — | — | EP | disclosed |
| CN-117136188-A | Process for preparing enantiomerically enriched forms of 2- [2- (2-chlorothiazol-5-yl) -2-hydroxyethyl ] sulfanyl-6-hydroxy-3-methyl-5-phenylpyrimidin-4-one by hydrogenation of 2-oxo derivatives in the presence of chiral transition metal catalysts | 巴斯夫欧洲公司 | 2023-11-28 | — | — | CN | disclosed |
| WO-2023135582-A1 | NEW STEREORETENTIVE RUTHENIUM COMPLEXES, METHOD OF THEIR PREPARATION, INTERMEDIATES USED IN THIS METHOD AND USE OF NEW STEREORETENTIVE RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS | UNIWERSYTET WARSZAWSKI (PL) | 2023-07-20 | — | — | WO | disclosed |
| CN-116396791-A | Lubricant composition and bearing | 国立大学法人山梨大学 | 2023-07-07 | — | — | CN | disclosed |
| EP-3820609-B1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | APEIRON SYNTHESIS SA (PL) | 2023-06-28 | — | — | EP | disclosed |
| CN-110291849-B | Wiring forming method | 日产化学株式会社 | 2023-06-06 | — | — | CN | disclosed |
| CN-114854472-B | Conductive lubricant | 国立大学法人山梨大学 | 2023-06-02 | — | — | CN | disclosed |
| US-20150298111-A1 | Ruthenium Or Osmium Complex, Method For Its Preparation And Use Thereof | Instytut Chemii Organicznej Polskiej Akademii Nauk (PL) | 2015-10-22 | — | — | US | disclosed |
| US-9074028-B2 | Complexes of ruthenum, method for their preparation, and their application in olefin metathesis reactions | UMICORE AG & CO. KG (DE) | 2015-07-07 | — | — | US | disclosed |
| WO-2014102622-A1 | NOVEL RUTHENIUM COMPLEXES, A METHOD OF PRODUCING THEM, AND THEIR USE IN OLEFIN METATHESIS | INSTYTUT CHEMII ORGANICZNEJ PAN (PL) | 2014-07-03 | — | — | WO | disclosed |
| US-20140171607-A1 | New Complexes of Ruthenium, Method for Their Preparation, and Their Application in Olefin Metathesis Reactions | UMICORE AG & CO. KG (DE) | 2014-06-19 | — | — | US | disclosed |
| US-8022205-B2 | Pyrimidine derivatives as PI3K inhibitor and use thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100324284-A1 | PYRROLOPYRIMIDINE DERIVATIVE AS P13K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2010-12-23 | — | — | US | disclosed |
| WO-2010117796-A2 | PROCESSES FOR THE PREPARATION OF ALPHA-CHLOROKETONES FROM CARBOXYLIC ACIDS | CODEXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-2239261-A1 | PYRROLOPYRIMIDIN DERIVATIVE FOR USE AS PI3K INHIBITOR, AND USE THEREOF | Chugai Seiyaku Kabushiki Kaisha (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2050749-A1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-22 | — | — | EP | disclosed |