Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 5/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12715453 | 0.81 | USP30 (0.43) | USP30LPLLIPGP2RX7FFAR1 | |
| Hydrochloric Acid SCHEMBL16936712 | 0.78 | USP30 (0.41) | USP30LPLLIPGP2RX7L3MBTL1 | |
| SCHEMBL16186833 | 0.77 | USP30 (0.46) | USP30FFAR1 | |
| SCHEMBL26276543 | 0.77 | USP30 (0.46) | USP30P2RX7MAPK1 | |
| SCHEMBL2699306 | 0.77 | USP30 (0.43) | USP30 | |
| SCHEMBL21773957 | 0.77 | USP30 (0.52) | USP30 | |
| SCHEMBL23390205 | 0.75 | USP30 (0.42) | USP30LPLLIPGFFAR1 | |
| SCHEMBL22971076 | 0.75 | USP30 (0.40) | USP30LPLLIPGFFAR1 | |
| SCHEMBL7882060 | 0.75 | USP30 (0.40) | USP30P2RX7MAPK1 | |
| SCHEMBL14844673 | 0.74 | USP30 (0.47) | USP30FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319943-B1 | NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-10239859-B2 | Nitrogen-containing heterocycles as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-26 | — | — | US | disclosed |
| US-20180201600-A1 | NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | US | disclosed |
| US-8518945-B2 | Pyrrolopyrazine kinase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8518945-B2 | Pyrrolopyrazine kinase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8518945-B2 | Pyrrolopyrazine kinase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2550273-A2 | PYRROLOPYRAZINE KINASE INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011117145-A2 | PYRROLOPYRAZINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-09-29 | — | — | WO | disclosed |
| US-20110230462-A1 | Pyrrolopyrazine Kinase Inhibitors | HENDRICKS ROBERT THAN | 2011-09-22 | — | — | US | disclosed |
| US-20110230462-A1 | Pyrrolopyrazine Kinase Inhibitors | HENDRICKS ROBERT THAN | 2011-09-22 | — | — | US | disclosed |
| US-20110230462-A1 | Pyrrolopyrazine Kinase Inhibitors | HENDRICKS ROBERT THAN | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230462-A1 | Pyrrolopyrazine Kinase Inhibitors | SYK, ZAP70, BTK | USP30 1194/4885LPL 4542/4885LIPG 3995/4885 |
| US-20180201600-A1 | NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES | DDT, DNPH1, PTMS | USP30 2991/4885LPL 4562/4885LIPG 4630/4885 |
| US-10239859-B2 | Nitrogen-containing heterocycles as pesticides | DDT, DNPH1, PTMS | USP30 2991/4885LPL 4562/4885LIPG 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.