Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550934 | 0.90 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29842189 | 0.86 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL21797182 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL20550771 | 0.84 | NR3C2 (0.57) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20551157 | 0.82 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550936 | 0.82 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29842089 | 0.82 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL23795663 | 0.82 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL28609334 | 0.81 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL20550768 | 0.80 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877383-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASES | The University of Melbourne (AU) | 2021-09-15 | — | — | EP | disclosed |