Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.60 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.49 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394331 | 0.90 | MAPK14 (0.62) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL28400055 | 0.86 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL28391816 | 0.84 | MAPK14 (0.55) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL28393104 | 0.83 | MAPK14 (0.63) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL28391796 | 0.82 | MAPK14 (0.62) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL23795665 | 0.81 | MAPK14 (0.56) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL23795663 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL29842089 | 0.81 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL28610584 | 0.81 | MAPK14 (0.60) | MAPK14TGFBR1MAPK13MAPK12MAPK11 | |
| SCHEMBL28396556 | 0.80 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272298-A | Compounds and compositions for the treatment of respiratory diseases | 墨尔本大学 | 2021-08-17 | — | — | CN | disclosed |