Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 19/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375895 | 0.84 | APLNR (0.48) | APLNR | |
| SCHEMBL19375987 | 0.83 | APLNR (0.55) | APLNR | |
| SCHEMBL19375964 | 0.79 | APLNR (0.57) | APLNR | |
| SCHEMBL19376127 | 0.79 | APLNR (0.64) | APLNR | |
| SCHEMBL19376129 | 0.79 | APLNR (0.64) | APLNR | |
| SCHEMBL19376182 | 0.79 | APLNR (0.55) | APLNR | |
| SCHEMBL19375862 | 0.78 | APLNR (0.55) | APLNR | |
| SCHEMBL19375981 | 0.78 | APLNR (0.56) | APLNR | |
| SCHEMBL19376089 | 0.77 | APLNR (0.54) | APLNR | |
| SCHEMBL19376226 | 0.77 | APLNR (0.54) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433247-B1 | 6-HYDROXY-4-OXO-1,4-DIHYDROPYRIMIDINE-5-CARBOXAMIDES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-08 | — | — | EP | disclosed |