Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BIRC3 | Q13489 | 5/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829516 | 1.00 | XIAP (0.42) | XIAPLMNABIRC3BIRC2ALDH1A1 | |
| SCHEMBL1831421 | 0.82 | XIAP (0.41) | XIAPLMNABIRC3BIRC2ALDH1A1 | |
| SCHEMBL1829349 | 0.82 | XIAP (0.41) | XIAPLMNABIRC3BIRC2ALDH1A1 | |
| SCHEMBL1829444 | 0.80 | BIRC2 (0.41) | XIAPLMNABIRC2KMT2AF10 | |
| SCHEMBL1828707 | 0.80 | BIRC2 (0.41) | XIAPLMNABIRC2KMT2AF10 | |
| SCHEMBL1829728 | 0.78 | POLB (0.42) | XIAPLMNABIRC2KMT2AF10 | |
| SCHEMBL2379021 | 0.78 | POLB (0.42) | XIAPLMNABIRC2KMT2AF10 | |
| SCHEMBL9609049 | 0.77 | XIAP (0.48) | XIAPBIRC3BIRC2ALDH1A1MEN1 | |
| SCHEMBL1829020 | 0.75 | LMNA (0.38) | XIAPLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1828385 | 0.75 | LMNA (0.38) | XIAPLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230419-A1 | IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230419-A1 | IAP BINDING COMPOUNDS | BIRC5, BIRC7, BIRC3 | XIAP 4/4885LMNA 518/4885BIRC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.