Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23796144 | 1.00 | HDAC6 (0.52) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796332 | 1.00 | HDAC6 (0.52) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796438 | 0.92 | LMNA (0.47) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL28922738 | 0.92 | LMNA (0.47) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL28624302 | 0.92 | LMNA (0.47) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796204 | 0.92 | NPC1 (0.45) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796081 | 0.92 | NPC1 (0.45) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796082 | 0.92 | NPC1 (0.45) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23796314 | 0.91 | NPC1 (0.44) | HDAC6HDAC4NPC1RAB9ANPSR1 | |
| SCHEMBL23795905 | 0.90 | NPSR1 (0.57) | HDAC6HDAC4NPSR1HDAC8SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117835978-A | Pharmaceutical combinations comprising TEAD inhibitors and their use for cancer treatment | 诺华股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |