⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972383 | 0.73 | — | — | |
| SCHEMBL18309286 | 0.73 | — | — | |
| SCHEMBL23314206 | 0.72 | — | — | |
| SCHEMBL13941424 | 0.71 | — | — | |
| SCHEMBL12899516 | 0.71 | — | — | |
| SCHEMBL12427439 | 0.67 | — | — | |
| SCHEMBL17775028 | 0.61 | — | — | |
| SCHEMBL19078931 | 0.61 | — | — | |
| SCHEMBL17124623 | 0.61 | — | — | |
| SCHEMBL20324266 | 0.61 | OGA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178885-A1 | MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES AND USES THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |