Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23778393 | 0.88 | OPRL1 (0.49) | OPRL1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL20073889 | 0.83 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL29709377 | 0.83 | OPRL1 (0.49) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23778259 | 0.78 | OPRL1 (0.45) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11636971 | 0.74 | ALDH1A1 (0.54) | OPRL1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL23778457 | 0.72 | ALDH1A1 (0.52) | OPRL1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL23798589 | 0.71 | CHRM1 (0.43) | OPRL1 | |
| SCHEMBL29709369 | 0.69 | CHRM1 (0.44) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23799154 | 0.69 | CHRM1 (0.44) | OPRL1OPRM1OPRK1 | |
| SCHEMBL20073887 | 0.69 | CHRM1 (0.44) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526207-B1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-08 | — | — | EP | disclosed |