Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27435747 | 0.98 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL27434839 | 0.94 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL517051 | 0.90 | HDAC3 (0.87) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL23798525 | 0.90 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22923581 | 0.87 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17252161 | 0.87 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL8322074 | 0.87 | HDAC3 (0.66) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL20105007 | 0.86 | HDAC1 (0.97) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26553751 | 0.85 | ENPP2 (0.61) | ENPP2DGAT2HPGDCA1CA2 | |
| SCHEMBL26553753 | 0.85 | ENPP2 (0.61) | ENPP2DGAT2HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178818-A2 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-09-10 | — | — | WO | disclosed |