SCHEMBL23799239

SCHEMBL23799239

CC1=C/c2c(sc3ccccc23)/C=C\C=C\1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.39
ALDH1A1 P00352 4/20 0.36
MAPT P10636 2/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
IDO1 P14902 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ROCK1 Q13464 1/20 0.31
TDO2 P48775 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FTO Q9C0B1 1/20 0.31
RAB9A P51151 2/20 0.30
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545120 0.73 GPR3 (0.52) GPR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL24361582 0.72 GPR3 (0.35) GPR3ALDH1A1
SCHEMBL23430324 0.71 GPR3 (0.38) GPR3ALDH1A1MAPTIDO1ROCK1
SCHEMBL13445703 0.70 GPR3 (0.40) GPR3ALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL19299443 0.70 GPR3 (0.40) GPR3ALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL24295804 0.70 GPR3 (0.33) GPR3
SCHEMBL17528782 0.67 GPR3 (0.40) GPR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL19721212 0.66 GPR3 (0.43) GPR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL278665 0.66 GPR3 (0.43) GPR3ALDH1A1MAPTMEN1KMT2A
SCHEMBL24061452 0.65 GPR3 (0.34) GPR3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3546453-B1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME LG CHEMICAL LTD (KR) 2021-09-08 EP disclosed