Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073819 | 0.89 | GRM5 (0.45) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL17827959 | 0.86 | GRM5 (0.41) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL11525180 | 0.84 | GRM5 (0.41) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6634184 | 0.82 | GRM5 (0.40) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21281619 | 0.82 | GRM5 (0.40) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL23798616 | 0.82 | GRM5 (0.54) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| Bromide SCHEMBL6633796 | 0.81 | GRM5 (0.39) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31510053 | 0.80 | TRPV1 (0.41) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL317954 | 0.80 | AOC1 (0.43) | GRM5ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL20457772 | 0.80 | GRM5 (0.37) | GRM5ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526207-B1 | HETEROCYCLIC COMPOUNDS HAVING ACTIVITY AS MODULATORS OF MUSCARINIC M1 AND/OR M4 RECEPTORS IN THE TREATMENT OF CNS DISEASES AND PAINS. | HEPTARES THERAPEUTICS LTD (GB) | 2021-09-08 | — | — | EP | disclosed |