SCHEMBL23801799

SCHEMBL23801799

CCOC(=O)Oc1ccc(C(=O)c2ccc3c(c2)c2cc(C)ccc2n3CC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 4/20 0.47
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
CNR2 P34972 1/20 0.41
KDM4E B2RXH2 5/20 0.41
HPGD P15428 3/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25515593 0.85 CNR2 (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23802405 0.84 CNR2 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23802413 0.84 CNR2 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13150979 0.81 CNR2 (0.60) RORCTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL23801803 0.81 CNR2 (0.41) RORCTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25515766 0.80 RORC (0.38) RORCTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5797538 0.80 MAPT (0.55) RORCKDM4EHPGDHTTMAPT
SCHEMBL25515599 0.80 CNR2 (0.42) RORCTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9459043 0.79 PTGER4 (0.55) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25515634 0.78 CNR2 (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021175855-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-09-10 WO disclosed