Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | F3 | P13726 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | OXTR | P30559 | 1/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.57 |
| ▸ | CD81 | P60033 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | USP7 | Q93009 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049549 | 0.90 | PTPN1 (0.74) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL28126637 | 0.90 | PTPN1 (0.74) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL5795870 | 0.90 | PTPN1 (0.74) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL1048326 | 0.83 | F3 (0.73) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| Methyl Echinocystate SCHEMBL17030530 | 0.83 | F3 (0.82) | PTPN1F3CYP3A4MAPK1OXTR | |
| SCHEMBL5796282 | 0.83 | F3 (0.73) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL5798114 | 0.82 | PTPN1 (0.65) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL5798116 | 0.82 | PTPN1 (0.65) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL2597674 | 0.81 | F3 (0.79) | PTPN1ALOX5F3CYP3A4MAPK1 | |
| SCHEMBL13629636 | 0.81 | F3 (0.79) | PTPN1ALOX5F3CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284677-A1 | NOVEL TRITERPENE SAPONIN DERIVATIVE AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284677-A1 | NOVEL TRITERPENE SAPONIN DERIVATIVE AND USE THEREOF | GRAMD1A, STARD7, STARD10 | PTPN1 3552/4885ALOX5 3423/4885F3 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.