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Sugi Predict / Targets / GRAMD1A

GRAMD1A

Protein Aster-A · Q96CP6 · GRAMD1A on Sugi Atlas →

5,715 patent compounds predicted against GRAMD1A, 4,072 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL19451180 SCHEMBL19451180 0.63 6/20
SCHEMBL19585916 SCHEMBL19585916 0.56 6/20
SCHEMBL19585318 SCHEMBL19585318 0.53 6/20
SCHEMBL17553379 SCHEMBL17553379 0.51 6/20
SCHEMBL20234364 SCHEMBL20234364 0.51 6/20
SCHEMBL12301883 SCHEMBL12301883 0.49 6/20
SCHEMBL19585797 SCHEMBL19585797 0.47 6/20
SCHEMBL13622232 SCHEMBL13622232 0.44 6/20
SCHEMBL5958951 SCHEMBL5958951 0.39 6/20
SCHEMBL19503737 SCHEMBL19503737 0.62 5/20
SCHEMBL19451178 SCHEMBL19451178 0.57 5/20
SCHEMBL20128982 SCHEMBL20128982 0.53 5/20
SCHEMBL20203270 SCHEMBL20203270 0.48 5/20
SCHEMBL20188786 SCHEMBL20188786 0.62 4/20
SCHEMBL20188589 SCHEMBL20188589 0.61 4/20
SCHEMBL20208029 SCHEMBL20208029 0.61 4/20
SCHEMBL19475570 SCHEMBL19475570 0.59 4/20
SCHEMBL17859116 SCHEMBL17859116 0.51 4/20
SCHEMBL18476414 SCHEMBL18476414 0.51 4/20
SCHEMBL20208270 SCHEMBL20208270 0.51 4/20

Clinical trials — most relevant to GRAMD1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
Validation of the RADIAL Algorithm for Diagnosis of Autosomal Recessive Cerebellar Ataxia nanRECRUITING
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Determinant of Foveolar Hypoplasia in Parents of Albinos Children nanCOMPLETED
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genetic Biomarkers for the Response to Anti-VEGF (Vascular Endothelial Growth Factor).Treatment in Wet Age-related Macular Degeneration (Wet ARMD) nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Italian Anderson Fabry Disease Cardiovascular Registry nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Genetic Aspects of Neurologic and Psychiatric Disorders nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias nanCOMPLETED
Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases nanACTIVE_NOT_RECRUITING
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Validation of a Clinical Algorithm for the Diagnosis of Recessive Ataxias nanCOMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Mayo AVC Registry and Biobank nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a GRAMD1A binder may also engage these)

ProteinNameSimilarity
Q8VEF1 — 1.000 Q8VEF1 →
Q3KR56 — 1.000 Q3KR56 →
Q0QWG9 — 0.980 Q0QWG9 →
A4D2P6 — 0.980 A4D2P6 →
P49797 — 0.979 P49797 →
P97492 — 0.977 P97492 →
Q66T02 — 0.977 Q66T02 →
Q923Q2 — 0.977 Q923Q2 →
Q9ER64 — 0.977 Q9ER64 →
Q8VDV3 — 0.976 Q8VDV3 →
P70268 — 0.976 P70268 →
Q9BZF2 — 0.975 Q9BZF2 →
Q60875 — 0.975 Q60875 →
O08773 — 0.975 O08773 →
Q9H0X9 — 0.975 Q9H0X9 →
Q9DC04 — 0.974 Q9DC04 →
Q8TBN0 — 0.974 Q8TBN0 →
Q9Z206 — 0.974 Q9Z206 →
PKN1 Serine/threonine-protein kinase N1 0.974 landscape →
O43566 — 0.974 O43566 →
G9CGD6 — 0.974 G9CGD6 →
Q6DRP4 — 0.974 Q6DRP4 →
B2DCZ9 — 0.974 B2DCZ9 →
Q2KJ58 — 0.974 Q2KJ58 →
Q5FVC2 — 0.973 Q5FVC2 →
Q8BL80 — 0.973 Q8BL80 →
Q3KR37 — 0.973 Q3KR37 →
Q9UPU7 — 0.973 Q9UPU7 →
Q5SNT2 — 0.973 Q5SNT2 →
Q8C190 — 0.973 Q8C190 →