SCHEMBL23802477

CCCCCCC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(OCCOC)C1OP(=O)(O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C(OCCOC)[C@H]1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C(OCCOC)C1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C(OCCOC)C1O

nearest known ligand 0.50

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	DTYMK	P23919	4/20	0.50

▸	TERT	O14746	1/20	0.50

▸	F2	P00734	2/20	0.47

▸	RNASEL	Q05823	8/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18672491	1.00	DTYMK (0.50)	DTYMKTERTF2RNASEL
SCHEMBL19681292	1.00	DTYMK (0.51)	DTYMKTERTF2RNASEL
SCHEMBL18993997	0.99	DTYMK (0.51)	DTYMKTERTF2RNASEL
SCHEMBL23801884	0.99	DTYMK (0.51)	DTYMKTERTF2RNASEL
SCHEMBL23801876	0.98	DTYMK (0.53)	DTYMKTERTF2RNASEL
SCHEMBL23801880	0.96	DTYMK (0.54)	DTYMKTERTRNASEL
SCHEMBL19681267	0.96	TERT (0.47)	DTYMKTERTF2RNASEL
SCHEMBL24425689	0.96	DTYMK (0.55)	DTYMKTERTRNASEL
SCHEMBL16410999	0.95	DTYMK (0.54)	DTYMKRNASEL
SCHEMBL18159194	0.95	DTYMK (0.53)	DTYMKTERTF2RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20210277397-A1	COMPOUNDS AND METHODS FOR MODULATING UBE3A-ATS	IONIS PHARMACEUTICALS, INC. (US)	2021-09-09	—	—	US	disclosed