Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 16/20 | 0.41 |
| ▸ | NPY1R | P25929 | 10/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.41 |
| ▸ | NPY2R | P49146 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287945 | 0.89 | GNPAT (0.50) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL25098291 | 0.88 | NPY4R (0.40) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL23258921 | 0.85 | SIRT5 (0.55) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL8500280 | 0.85 | NPY4R (0.37) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL13410388 | 0.85 | NPY4R (0.37) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL15698292 | 0.85 | SIRT5 (0.45) | SIRT5NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL23104857 | 0.84 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21933744 | 0.84 | NPY4R (0.39) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL15145773 | 0.83 | NPY4R (0.47) | SIRT5GNPATNPY4RNPY1RNPY5R | |
| SCHEMBL25098831 | 0.83 | NPY4R (0.37) | SIRT5GNPATNPY4RNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178887-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR MODIFYING CAR-T CELL ACTIVITY | PURDUE RESEARCH FOUNDATION (US) | 2021-09-10 | — | — | WO | disclosed |