SCHEMBL23804445

SCHEMBL23804445

Cc1nn(C)c(Nc2c(F)cc(Cl)cc2[N+](=O)[O-])c1-c1ccc(F)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
LMNA P02545 3/20 0.37
HSD11B1 P28845 3/20 0.36
SLC34A1 Q06495 4/20 0.36
TDP1 Q9NUW8 2/20 0.34
S1PR4 O95977 1/20 0.33
P2RX7 Q99572 1/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATM Q13315 1/20 0.33
IGF1R P08069 1/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30211204 1.00 MAPT (0.40) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL30211195 0.94 MAPT (0.42) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL23804435 0.94 MAPT (0.42) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL23804439 0.93 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL29627682 0.93 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL20680807 0.92 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL27212613 0.92 MAPT (0.38) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL23804421 0.90 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL29627689 0.90 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1
SCHEMBL23804431 0.89 MAPT (0.39) MAPTLMNAHSD11B1SLC34A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112969688-B Fungicidal nitroaniline-substituted pyrazoles FMC公司 2024-06-04 CN claimed
EP-3847160-B1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORP (US) 2024-05-08 EP claimed
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION 2023-05-18 US claimed
EP-4118072-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION (US) 2023-01-18 EP claimed
CN-115605461-A Fungicidal mixtures containing pyrazole derivatives FMC公司(US) 2023-01-13 CN claimed
US-20210317087-A1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORPORATION 2021-10-14 US claimed
WO-2021183721-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES. FMC CORPORATION (US) 2021-09-16 WO claimed
CN-112969688-A Fungicidal nitroaniline substituted pyrazoles FMC公司 2021-06-15 CN claimed
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles FMC CORPORATION (US) 2025-08-26 US disclosed
EP-4388876-A2 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC Corporation (US) 2024-06-26 EP disclosed
CN-112969688-B Fungicidal nitroaniline-substituted pyrazoles FMC公司 2024-06-04 CN disclosed
EP-3847160-B1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORP (US) 2024-05-08 EP disclosed
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION 2023-05-18 US disclosed
EP-4118072-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION (US) 2023-01-18 EP disclosed
CN-115605461-A Fungicidal mixtures containing pyrazole derivatives FMC公司(US) 2023-01-13 CN disclosed
US-20210317087-A1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORPORATION 2021-10-14 US disclosed
WO-2021183721-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES. FMC CORPORATION (US) 2021-09-16 WO disclosed
CN-112969688-A Fungicidal nitroaniline substituted pyrazoles FMC公司 2021-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES CYP1B1, CYP4B1, TH MAPT 134/4885LMNA 3149/4885HSD11B1 958/4885
US-20210317087-A1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES TH, NOX1, NOX3 MAPT 216/4885LMNA 3962/4885HSD11B1 1144/4885
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles TH, NOX1, NOX3 MAPT 216/4885LMNA 3962/4885HSD11B1 1144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.