SCHEMBL2380451

SCHEMBL2380451

N[C@H](CC1CC1)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75669 1.00
SCHEMBL75670 1.00
Hydrochloric Acid SCHEMBL21058970 0.98 ANPEP (0.46)
Hydrochloric Acid SCHEMBL21058967 0.98 ANPEP (0.46)
SCHEMBL24520174 0.91 CPB2 (0.45)
SCHEMBL11218011 0.91 ANPEP (0.42)
SCHEMBL5103970 0.91 CPB2 (0.45)
SCHEMBL24520198 0.91 PLG (0.52)
SCHEMBL9182828 0.91 CPB2 (0.45)
SCHEMBL1578235 0.91 ANPEP (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772230-A Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2024-10-15 CN claimed
CN-114615976-A Kappa opioid receptor peptide amide agonists 人福医药美国公司 2022-06-10 CN claimed
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 US disclosed
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 EP disclosed
EP-4598914-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 Tocris Cookson Limited (GB) 2025-08-13 EP disclosed
US-20250243196-A1 CITRON KINASE INHIBITORS THE CLEVELAND CLINIC FOUNDATION 2025-07-31 US disclosed
US-12344605-B2 Substituted pyrrolidine amides II GRUENENTHAL GMBH (DE) 2025-07-01 US disclosed
US-20250197360-A1 NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE BARUCH S. BLUMBERG INSTITUTE 2025-06-19 US disclosed
CN-119072467-A Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof 巴鲁克斯布伦博格研究所 2024-12-03 CN disclosed
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2024-11-19 US disclosed
CN-118772230-A Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2024-10-15 CN disclosed
US-5614498-A OLIGOPEPTIDES, BRONCHDILATORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-03-25 US disclosed
US-5614625-A COLLAGENASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 1997-03-25 US disclosed
EP-0763013-A1 HYDROXYLAMINE DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS F. HOFFMANN-LA ROCHE AG (CH) 1997-03-19 EP disclosed
US-5508272-A SELECTIVE ACE INHIBITORS, HYPOTENSIVE AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-04-16 US disclosed
US-5496928-A Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-03-05 US disclosed
WO-1995033709-A1 HYDROXYLAMINE DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS F. HOFFMANN-LA ROCHE AG (CH) 1995-12-14 WO disclosed
EP-0684240-A1 Hydroxamic acid derivatives with tricyclic substitution F. HOFFMANN-LA ROCHE AG (CH) 1995-11-29 EP disclosed
EP-0629627-A2 Bicyclic carboxylic acids and their derivatives as nep and aca inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1994-12-21 EP disclosed
EP-0555537-A2 Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-18 EP disclosed