Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 15/20 | 1.00 |
| ▸ | HSPA2 | P54652 | 6/20 | 1.00 |
| ▸ | HSPA9 | P38646 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HSPA1A | P0DMV8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23804612 | 1.00 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804614 | 1.00 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23818889 | 0.89 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804606 | 0.88 | HSPA5 (0.78) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804615 | 0.85 | HSPA5 (0.74) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804607 | 0.85 | HSPA5 (0.74) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804623 | 0.82 | HSPA5 (0.72) | HSPA5HSPA2HSPA9HSPA8HSPA1A | |
| SCHEMBL23818887 | 0.82 | HSPA5 (1.00) | HSPA5HSPA2HSPA9HSPA1A | |
| SCHEMBL23804598 | 0.82 | HSPA5 (0.69) | HSPA5HSPA2HSPA9HTTHSPA8 | |
| SCHEMBL23804601 | 0.82 | HSPA5 (0.69) | HSPA5HSPA2HSPA9HTTHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230091297-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-03-23 | — | — | US | disclosed |
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230091297-A1 | INHIBITORS OF HSP70 PROTEINS | HSPA2, HSP90AB2P, HSP90AB1 | HSPA5 14/4885HSPA2 1/4885HSPA9 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.