⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380605 | 1.00 | — | — | |
| SCHEMBL2378583 | 0.80 | DPP4 (0.30) | — | |
| SCHEMBL2378585 | 0.80 | DPP4 (0.30) | — | |
| SCHEMBL20480027 | 0.74 | — | — | |
| SCHEMBL836062 | 0.74 | — | — | |
| SCHEMBL2379470 | 0.74 | — | — | |
| SCHEMBL1642178 | 0.72 | — | — | |
| SCHEMBL837055 | 0.71 | — | — | |
| SCHEMBL12619099 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL7939966 | 0.66 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212967-A1 | IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS | INCYTE CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |