SCHEMBL23807

SCHEMBL23807

COc1ccccc1B(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 1.00
ORAI1 Q96D31 1/20 0.78
ORAI2 Q96SN7 1/20 0.78
ORAI3 Q9BRQ5 1/20 0.78
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
CA7 P43166 3/20 0.57
CA9 Q16790 3/20 0.57
CA12 O43570 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA4 P22748 1/20 0.57
LIPE Q05469 1/20 0.53
TP53 P04637 2/20 0.52
TSHR P16473 1/20 0.52
ALDH1A1 P00352 3/20 0.46
ADRA2B P18089 1/20 0.46
PTGS1 P23219 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466484 1.00 ENPP2 (1.00) ENPP2ORAI1ORAI2ORAI3CA1
Ethane SCHEMBL3949093 0.98 ENPP2 (0.95) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL1360650 0.89 ENPP2 (0.80) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL6605244 0.86 ENPP2 (0.75) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL14700647 0.86 ENPP2 (0.75) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL19147471 0.86 ENPP2 (0.75) ENPP2ORAI1ORAI2ORAI3CA1
Tetrahydrofuran SCHEMBL28548585 0.84 ENPP2 (0.71) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL28107367 0.84 ENPP2 (0.71) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL30868961 0.84 ENPP2 (0.72) ENPP2ORAI1ORAI2ORAI3CA1
SCHEMBL23193854 0.82 ENPP2 (0.69) ENPP2ORAI1ORAI2ORAI3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6938 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-20250066381-A1 ONE-POT, MULTI-COMPONENT MANUFACTURING METHOD FOR TETRAHYDROTHIENOPYRIDINE DERIVATIVES INCLUDING N-SUBSTITUTED AMINO ACIDS MOLECULES & MATERIALS (KR) 2025-02-27 US claimed
US-12188898-B2 Non-enzymatic electrochemical sensor for measuring analytes TERUMO KABUSHIKI KAISHA (JP) 2025-01-07 US claimed
CN-119264060-A 6-Morpholine-N, 2-diphenyl pyrimidine-4-carboxamide compound and preparation method and application thereof 浙江科技大学 2025-01-07 CN claimed
CN-118420578-A Preparation method of 1-chlorodibenzofuran 濮阳惠成电子材料股份有限公司 2024-08-02 CN claimed
CN-114773161-B (4E) -1-fluoro-2, 5-diaryl-4-pentene-2-ol derivative and synthetic method thereof 华南理工大学 2024-01-30 CN claimed
CN-113444125-B Phosphoramidite ligand, preparation method thereof and application thereof in asymmetric carbonylation reaction 西北大学 2024-01-26 CN claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO claimed
EP-1107982-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-$i(CIS)-DIOL CYCLIC-PEPTIDES Eli Lilly & Company (US) 2001-06-20 EP claimed
EP-1041071-A1 Methods for the preparation of coumarine derivatives LIGAND PHARMACEUTICALS INCORPORATED (US) 2000-10-04 EP claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
WO-2000012540-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-CIS-DIOL CYCLIC-PEPTIDES ELI LILLY AND COMPANY (US) 2000-03-09 WO claimed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO claimed
CN-1222161-A Process for preparing certain aza cyclohexapeptides MERCK & CO INC (US) 1999-07-07 CN claimed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 EP claimed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 WO claimed
US-4409391-A Process to produce anthracycline compounds HOFFMANN-LA ROCHE INC. (US) 1983-10-11 US claimed