Methacrylic Acid

Methacrylic Acid

SCHEMBL2380710

C=C(C(=O)OCCCC)C1CO1.C=C(C)C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.37
POLB P06746 2/20 0.36
HTT P42858 2/20 0.36
APEX1 P27695 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 2/20 0.36
ATM Q13315 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 1/20 0.34
THRA P10827 1/20 0.34
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378759 0.86 TSHR (0.57) TSHRALDH1A1HTTTDP1THRB
Methacrylic Acid SCHEMBL544618 0.81 KDM4E (0.51) TSHRALDH1A1HPGDPOLBTDP1
SCHEMBL3951769 0.80 TSHR (0.45) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL11696629 0.80 ALDH1A1 (0.69) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL8406971 0.79 TSHR (0.75) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL8427966 0.79 TSHR (0.75) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL9422682 0.79 TSHR (0.75) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL462262 0.79 TSHR (0.75) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL29038218 0.77 TSHR (0.72) TSHRALDH1A1HPGDPOLBHTT
Methacrylic Acid SCHEMBL28398525 0.76 TSHR (0.70) TSHRALDH1A1HPGDPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017290-B2 Stable toner transferability; utilizing intermediate member; fixability, high quality images RICOH COMPANY, LTD. (JP) 2011-09-13 US disclosed
US-20080226997-A1 IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2008-09-18 US disclosed