Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.49 |
| ▸ | POLG | P54098 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23425434 | 1.00 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL27267581 | 0.88 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL15788423 | 0.88 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL15259219 | 0.88 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL18837710 | 0.88 | LMNA (0.52) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL24872399 | 0.88 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL12149545 | 0.88 | LMNA (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL20056930 | 0.86 | LMNA (0.52) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL21895836 | 0.85 | POLG (0.49) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL24229283 | 0.84 | LMNA (0.46) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981542-B1 | 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2021-09-15 | — | — | EP | disclosed |