Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24877169 | 0.93 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23106243 | 0.93 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23809335 | 0.91 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23106232 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL23106236 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23879759 | 0.85 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23879728 | 0.85 | F10 (0.39) | ALDH1A1GAAMAPTF10KMT2A | |
| SCHEMBL22327072 | 0.85 | MAOB (0.37) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23106278 | 0.84 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1GAAMAPTF10 | |
| SCHEMBL23106219 | 0.83 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1GAAMAPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284975-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2021-09-16 | — | — | US | disclosed |