Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.41 |
| ▸ | CNR1 | P21554 | 17/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743834 | 0.77 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL23126508 | 0.71 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL18879810 | 0.71 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL19251082 | 0.70 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL19251045 | 0.70 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL18516932 | 0.70 | CNR2 (0.45) | CNR2CNR1 | |
| SCHEMBL15692490 | 0.70 | PTGS2 (0.42) | — | |
| SCHEMBL22024369 | 0.69 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL18793227 | 0.69 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL9324343 | 0.69 | CNR1 (0.50) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283138-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCL9 | CNR2 3259/4885CNR1 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.