Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23809607 | 0.92 | ALDH1A1 (0.30) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18535484 | 0.87 | ALDH1A1 (0.30) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193189 | 0.86 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL17677612 | 0.86 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL22240377 | 0.83 | — | — | |
| SCHEMBL23809613 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL17677694 | 0.82 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL18193241 | 0.82 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 | |
| SCHEMBL20107505 | 0.82 | — | — | |
| SCHEMBL19840279 | 0.81 | ALDH1A1 (0.32) | ALDH1A1CYP3A4CHRM1ALOX15ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532578-B1 | LUBRICANT ADDITIVE COMPOSITIONS COMPRISING PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORP (US) | 2021-09-15 | — | — | EP | disclosed |