Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149715 | 0.83 | KDM4E (0.40) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL23810141 | 0.82 | KDM4E (0.40) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL23810201 | 0.81 | KDM4E (0.45) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL15285087 | 0.78 | MAPK1 (0.53) | KDM4EKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL16560328 | 0.76 | KDM4E (0.41) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL23810206 | 0.76 | KDM4E (0.41) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL20804067 | 0.76 | KDM4E (0.38) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL27934649 | 0.75 | KDM4E (0.38) | KDM4ERAB9ANPC1KDM4CHDAC3 | |
| SCHEMBL15299581 | 0.75 | GABRA5 (0.45) | KDM4EKMT2AMEN1MAPT | |
| SCHEMBL15285036 | 0.75 | MAOB (0.44) | KDM4ERAB9ANPC1KDM4CHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | POLL, PCNA, DNMT3A | KDM4E 3663/4885RAB9A 4844/4885NPC1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.