Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | SAT1 | P21673 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865144 | 0.98 | SIGMAR1 (0.62) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL19508398 | 0.91 | CYP1A2 (0.58) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL8396180 | 0.91 | CYP1A2 (0.58) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL23675585 | 0.91 | CYP1A2 (0.58) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL23099440 | 0.89 | SAT1 (0.57) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL8392349 | 0.89 | SAT1 (0.52) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL23235475 | 0.86 | CYP1A2 (0.52) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL28106413 | 0.84 | — | — | |
| SCHEMBL7621214 | 0.84 | CYP1A2 (0.46) | SIGMAR1CYP1A2SAT1CYP2C19MEN1 | |
| SCHEMBL27435880 | 0.84 | SIGMAR1 (0.51) | SIGMAR1CYP1A2SAT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |