Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139502 | 0.95 | ALDH1A1 (0.62) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL26451268 | 0.85 | TDP1 (0.66) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL23812437 | 0.85 | ALDH1A1 (0.69) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL23812446 | 0.84 | TDP1 (0.60) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6282770 | 0.84 | KMT2A (0.81) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4993714 | 0.83 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL12856431 | 0.83 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20400389 | 0.83 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4311512 | 0.83 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20401024 | 0.83 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353152-B1 | METHOD | NORSK MEDISINSK SYKLOTRONSENTER AS (NO) | 2021-09-15 | — | — | EP | disclosed |