Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416586 | 0.82 | KCNQ3 (0.41) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL6726735 | 0.82 | KCNQ3 (0.41) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL29525674 | 0.82 | KCNQ3 (0.41) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL6726742 | 0.81 | KMT2A (0.50) | KDM4EMAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL19816909 | 0.81 | MAPK1 (0.53) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL19360803 | 0.80 | MAPK1 (0.37) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL10001386 | 0.80 | NAPRT (0.47) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL29815064 | 0.80 | NAPRT (0.47) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL24339409 | 0.79 | POLB (0.34) | ALDH1A1KDM4EHTTCA2CA4 | |
| SCHEMBL17544977 | 0.79 | ALOX5AP (0.41) | KDM4EMAPK1L3MBTL1MAOBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117714-A1 | IMAGING METHODS AND RADIOTRACERS FOR USE THEREIN | VESTLANDETS INNOVASJONS SELSKAP AS (VIS) (NO) | 2022-06-09 | — | — | WO | disclosed |
| EP-3222615-B1 | PSMA-BINDING AGENTS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-05-04 | — | — | EP | disclosed |
| EP-3183236-B1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WSS (DE) | 2022-04-20 | — | — | EP | disclosed |
| EP-3353152-B1 | METHOD | NORSK MEDISINSK SYKLOTRONSENTER AS (NO) | 2021-09-15 | — | — | EP | disclosed |
| EP-3222615-A1 | PSMA-BINDING AGENTS AND USES THEREOF | The Johns Hopkins University (US) | 2017-09-27 | — | — | EP | disclosed |