Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360825 | 0.82 | POLB (0.37) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL19360023 | 0.82 | POLB (0.37) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29525770 | 0.82 | POLB (0.37) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL17573509 | 0.81 | KMT2A (0.50) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL19360804 | 0.79 | POLB (0.36) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL23812490 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL5889663 | 0.76 | TDP1 (0.41) | POLBMEN1KMT2ATDP1KDM4E | |
| SCHEMBL19360004 | 0.74 | POLB (0.40) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL19816909 | 0.74 | MAPK1 (0.53) | POLBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL19360017 | 0.73 | POLB (0.37) | POLBGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183236-B1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WSS (DE) | 2022-04-20 | — | — | EP | disclosed |