Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 19/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987723 | 0.91 | HPGDS (0.48) | HPGDS | |
| SCHEMBL19021507 | 0.91 | HPGDS (0.48) | HPGDS | |
| SCHEMBL18987834 | 0.91 | HPGDS (0.48) | HPGDS | |
| SCHEMBL23812973 | 0.91 | HPGDS (0.48) | HPGDS | |
| SCHEMBL18987833 | 0.91 | HPGDS (0.48) | HPGDS | |
| SCHEMBL18988534 | 0.88 | HPGDS (0.54) | HPGDS | |
| SCHEMBL18988533 | 0.88 | HPGDS (0.54) | HPGDS | |
| SCHEMBL23812949 | 0.88 | HPGDS (0.55) | HPGDS | |
| SCHEMBL19021262 | 0.88 | HPGDS (0.55) | HPGDS | |
| SCHEMBL19019773 | 0.87 | HPGDS (0.55) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390384-B1 | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2021-09-15 | — | — | EP | disclosed |