Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 7/20 | 0.78 |
| ▸ | CBX7 | O95931 | 4/20 | 0.78 |
| ▸ | CBX8 | Q9HC52 | 4/20 | 0.78 |
| ▸ | CBX4 | O00257 | 3/20 | 0.78 |
| ▸ | CBX6 | O95503 | 1/20 | 0.64 |
| ▸ | CBX2 | Q14781 | 1/20 | 0.64 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510752 | 1.00 | CDYL2 (0.78) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL29613538 | 0.95 | CDYL2 (0.70) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL24510878 | 0.94 | CDYL2 (0.74) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL23718040 | 0.93 | CDYL2 (0.87) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL26219950 | 0.93 | CDYL2 (0.87) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL23682865 | 0.93 | CDYL2 (0.87) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL23682719 | 0.93 | CDYL2 (0.87) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL23717921 | 0.93 | CDYL2 (0.87) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL23682764 | 0.91 | CDYL2 (0.66) | CDYL2CBX7CBX8CBX4CBX6 | |
| SCHEMBL29129080 | 0.89 | CDYL2 (0.70) | CDYL2CBX7CBX8CBX4CBX6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284629-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284629-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | NEDD4, UBQLN2, UBTF | CDYL2 1159/4885CBX7 1599/4885CBX8 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.