CDYL2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4413088	0.56	10/20
SCHEMBL2950965	0.70	9/20
SCHEMBL4246933	0.52	8/20
SCHEMBL2953262	0.50	8/20
SCHEMBL4242148	0.56	7/20
SCHEMBL4944007	0.47	7/20
Bromide (SCHEMBL3845737)	0.52	6/20
Bromide (SCHEMBL3845745)	0.48	6/20
SCHEMBL1063151	0.43	6/20
SCHEMBL2829735	0.80	5/20
SCHEMBL3706421	0.50	5/20
Bromide (SCHEMBL3853584)	0.47	5/20
SCHEMBL4416757	0.43	5/20
SCHEMBL1061180	0.42	5/20
SCHEMBL2403057	0.64	4/20
SCHEMBL3026762	0.55	4/20
SCHEMBL4313102	0.52	4/20
SCHEMBL2953037	0.50	4/20
SCHEMBL4784997	0.49	4/20
SCHEMBL4413144	0.49	4/20

Clinical trials — most relevant to CDYL2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer	PHASE1/PHASE2	SUSPENDED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
Immunophenotyping and Xist Gene in AML	nan	UNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study	nan	RECRUITING
Genetic Studies Spermatogenic Failure	nan	COMPLETED
Development and Validation of a Nomogram for Predicting Surgery in Newly-diagnosed Crohn's Disease: a Retrospective Cohort Study	nan	COMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
Genomic Imprinting Testing for Diagnosis of Bladder Cancer	nan	UNKNOWN
Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome	nan	COMPLETED
Eating Behaviour in Crohn's Disease	nan	COMPLETED
X-chromosome Inactivation, Epigenetics and the Transcriptome	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes	nan	ACTIVE_NOT_RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Genomic Study of Congenital Malformation	nan	UNKNOWN
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Study of the Sex Differences in Inflammatory Diseases in Children	nan	UNKNOWN
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus	nan	ACTIVE_NOT_RECRUITING
A Study of the Genetic Analysis of Brain Disorders	nan	COMPLETED
Predictive Value of E-cadherin, β-catenin and SOX4 in Recurrence and/or Progression of Non-muscle Invasive Urinary Bladder Transitional Cell Carcinoma. A Retrospective Study	nan	COMPLETED
A Study of Multilocus Methylation Abnormalities in Subjects With Imprinting Disorders	nan	NOT_YET_RECRUITING
The Genetics of Chiari Type I Malformation	nan	COMPLETED
S9031-S9126-S9333-S9500-A, Studying Bone Marrow and Blood Samples From Patients With Acute Myeloid Leukemia	nan	COMPLETED
The Etiology and Progression of Brain Tumors	nan	COMPLETED
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer	nan	COMPLETED
A Prospective Study on the Application of Liquid Biopsy in the Surveillance of High-risk Population of HCC.	nan	UNKNOWN
Epidemiological and Genetic Studies of Body Mass Index	nan	COMPLETED
Risk Factors for the Development of Celiac Disease in Genetically Predisposed Children	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CDYL2 binder may also engage these)

Protein	Name	Similarity
Q9D5D8	—	1.000	Q9D5D8 →
CDYL	Chromodomain Y-like protein	0.995	landscape →
Q8BMD7	—	0.995	Q8BMD7 →
Q9C6G0	—	0.994	Q9C6G0 →
Q9Y6F7	—	0.994	Q9Y6F7 →
Q6AYK9	—	0.993	Q6AYK9 →
Q9M3B6	—	0.991	Q9M3B6 →
Q08BS4	—	0.990	Q08BS4 →
Q5TKR9	—	0.990	Q5TKR9 →
A4IHT0	—	0.990	A4IHT0 →
Q8TDB6	—	0.990	Q8TDB6 →
Q9LX30	—	0.989	Q9LX30 →
Q7TMI3	—	0.989	Q7TMI3 →
Q0WVW7	—	0.988	Q0WVW7 →
PIK3C2A	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0.988	landscape →
A2WYE9	—	0.988	A2WYE9 →
P34246	—	0.988	P34246 →
Q7XHR2	—	0.988	Q7XHR2 →
BRPF3	Bromodomain and PHD finger-containing protein 3	0.988	landscape →
KAT6A	Histone acetyltransferase KAT6A	0.988	landscape →
C8ZC77	—	0.988	C8ZC77 →
Q9D3R6	—	0.988	Q9D3R6 →
A8QFQ3	—	0.987	A8QFQ3 →
P46014	—	0.987	P46014 →
CDY1; CDY1B	Testis-specific chromodomain protein Y 1	0.987	landscape →
Q03460	—	0.987	Q03460 →
Q8L7T6	—	0.987	Q8L7T6 →
KATNAL2	Katanin p60 ATPase-containing subunit A-like 2	0.987	landscape →
Q8AXC7	—	0.987	Q8AXC7 →
Q6IVY4	—	0.987	Q6IVY4 →