Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803642 | 0.89 | GAA (0.60) | MEN1KMT2AGAASGMS2LRRK2 | |
| SCHEMBL30031887 | 0.89 | GAA (0.60) | MEN1KMT2AGAASGMS2LRRK2 | |
| SCHEMBL30032531 | 0.80 | GAA (0.56) | MEN1KMT2AGAASGMS2LRRK2 | |
| SCHEMBL30031861 | 0.80 | GAA (0.56) | MEN1KMT2AGAASGMS2LRRK2 | |
| SCHEMBL23803651 | 0.80 | GAA (0.56) | MEN1KMT2AGAASGMS2LRRK2 | |
| SCHEMBL23803632 | 0.76 | MCL1 (0.56) | MEN1KMT2AGAASGMS2MCL1 | |
| SCHEMBL30032553 | 0.76 | MCL1 (0.56) | MEN1KMT2AGAASGMS2MCL1 | |
| SCHEMBL30032667 | 0.76 | MCL1 (0.56) | MEN1KMT2AGAASGMS2MCL1 | |
| SCHEMBL2926378 | 0.73 | KDM4E (0.58) | MCL1MAOAMAOB | |
| SCHEMBL23809701 | 0.72 | SGMS2 (0.58) | MEN1KMT2AGAASGMS2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180655-A1 | 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS | OM PHARMA SA (CH) | 2021-09-16 | — | — | WO | disclosed |