Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEM1B | Q9UK73 | 3/20 | 0.62 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132888 | 1.00 | FEM1B (0.62) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817965 | 0.90 | FEM1B (0.59) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23804993 | 0.89 | FEM1B (0.67) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25455734 | 0.87 | FEM1B (0.60) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23818425 | 0.84 | FEM1B (0.57) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25455179 | 0.82 | FEM1B (0.48) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23817933 | 0.82 | FEM1B (0.48) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL25171623 | 0.82 | FEM1B (0.68) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23804989 | 0.81 | FEM1B (0.61) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30132890 | 0.81 | FEM1B (0.61) | FEM1BFNIP1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
| CN-115666538-A | FEM1B protein binding agents and uses thereof | 加利福尼亚大学董事会 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021183431-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | FEM1B 1/4885FNIP1 3/4885ALDH1A1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.