FEM1B

Protein fem-1 homolog B · Q9UK73 · FEM1B on Sugi Atlas →

160 patent compounds predicted against FEM1B, 136 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL25171623 SCHEMBL25171623 0.68 3/20
SCHEMBL23804993 SCHEMBL23804993 0.67 3/20
SCHEMBL23817980 SCHEMBL23817980 0.62 3/20
SCHEMBL30132888 SCHEMBL30132888 0.62 3/20
SCHEMBL23804989 SCHEMBL23804989 0.61 3/20
SCHEMBL30132890 SCHEMBL30132890 0.61 3/20
SCHEMBL23818422 SCHEMBL23818422 0.60 3/20
SCHEMBL25455734 SCHEMBL25455734 0.60 3/20
SCHEMBL23804984 SCHEMBL23804984 0.59 3/20
SCHEMBL23817965 SCHEMBL23817965 0.59 3/20
SCHEMBL23818590 SCHEMBL23818590 0.59 3/20
SCHEMBL30132893 SCHEMBL30132893 0.59 3/20
SCHEMBL23818425 SCHEMBL23818425 0.57 3/20
SCHEMBL23818554 SCHEMBL23818554 0.55 3/20
SCHEMBL23817939 SCHEMBL23817939 0.52 3/20
SCHEMBL23818387 SCHEMBL23818387 1.00 2/20
SCHEMBL30132892 SCHEMBL30132892 1.00 2/20
SCHEMBL25455185 SCHEMBL25455185 0.93 2/20
SCHEMBL25455775 SCHEMBL25455775 0.90 2/20
SCHEMBL23818550 SCHEMBL23818550 0.86 2/20

Clinical trials — most relevant to FEM1B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 PHASE1/PHASE2COMPLETED
Human MATER and Idiopathic Infertility nanCOMPLETED
Epidemiology of Pituitary Tumours: Prevalence of Associated Neoplasia nanUNKNOWN
Institution of an Italian Multicenter Database of Patients With Multiple Endocrine Neoplasia Type 1 (MENNET1 Database) nanNOT_YET_RECRUITING
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer nanCOMPLETED
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
The Genetics of Chiari Type I Malformation nanCOMPLETED
Genetic Analysis of Fraser Syndrome and Fryns Syndrome nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Study of Skeletal Disorders and Short Stature nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Microcephaly Genetic Deficiency in Neural Progenitors nanCOMPLETED
Genes Modulating the Severity of Aortic Aneurysms (MSF1-TGFBR2) nanUNKNOWN
Genetic Mechanisms and Additional Risk Factors Underlying Hip Dysplasia nanCOMPLETED
Familial Intracranial Aneurysm Study II nanCOMPLETED
Longitudinal Studies of Patient With FPDMM nanRECRUITING
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders nanRECRUITING
Stone Centre Urine and Serum Bank nanUNKNOWN
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Genetic Evaluation of Families With Endocrine Cancers nanCOMPLETED
A Study of Multilocus Methylation Abnormalities in Subjects With Imprinting Disorders nanNOT_YET_RECRUITING
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Stone Disease in Children and Their Families nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FEM1B binder may also engage these)

ProteinNameSimilarity
Q9Z2G0 1.000 Q9Z2G0 →
P0C6P7 1.000 P0C6P7 →
Q6GPE5 1.000 Q6GPE5 →
Q5ZM55 1.000 Q5ZM55 →
Q8CEF1 0.990 Q8CEF1 →
Q7T3P8 0.986 Q7T3P8 →
A7MB89 0.985 A7MB89 →
Q29RM5 0.983 Q29RM5 →
Q9Z2G1 0.982 Q9Z2G1 →
Q9BSK4 0.981 Q9BSK4 →
Q4V890 0.981 Q4V890 →
Q8C0T1 0.981 Q8C0T1 →
Q2T9K6 0.979 Q2T9K6 →
Q96JP0 0.979 Q96JP0 →
Q6P9Z4 0.979 Q6P9Z4 →
Q9Y574 0.975 Q9Y574 →
Q9WV71 0.974 Q9WV71 →
Q9VFD5 0.973 Q9VFD5 →
Q8VHS6 0.973 Q8VHS6 →
Q96Q27 0.973 Q96Q27 →
Q9H0C1 0.972 Q9H0C1 →
Q810B6 0.971 Q810B6 →
Q6P3X3 0.971 Q6P3X3 →
Q9Y575 0.971 Q9Y575 →
Q5R981 0.970 Q5R981 →
P0C927 0.970 P0C927 →
Q9P2R3 0.970 Q9P2R3 →
Q8HXA6 0.970 Q8HXA6 →
ATP6V1H V-type proton ATPase subunit H 0.970 landscape →
Q0IIZ5 0.970 Q0IIZ5 →