⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818584 | 0.97 | — | — | |
| SCHEMBL26333931 | 0.86 | RIPK1 (0.32) | — | |
| SCHEMBL23818945 | 0.86 | — | — | |
| SCHEMBL23819055 | 0.82 | RIPK1 (0.30) | — | |
| SCHEMBL26333018 | 0.82 | RIPK1 (0.30) | — | |
| SCHEMBL23818891 | 0.81 | — | — | |
| SCHEMBL26332933 | 0.80 | RIPK1 (0.31) | — | |
| SCHEMBL23819167 | 0.80 | RIPK1 (0.31) | — | |
| SCHEMBL23819180 | 0.80 | RIPK1 (0.31) | — | |
| SCHEMBL26333779 | 0.80 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284670-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-16 | — | — | US | disclosed |