SCHEMBL23819309

SCHEMBL23819309

CO[C@](C#N)(COP(=O)(N[C@@H](C)C(=O)OCC1CC1)Oc1ccccc1)[C@@H](OC(C)=O)[C@@H](OC(C)=O)c1ccc2c(N)ncnn12

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BTN3A1 O00481 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23819026 0.98 BTN3A1 (0.34) BTN3A1
SCHEMBL26332254 0.98 BTN3A1 (0.34) BTN3A1
SCHEMBL23818982 0.96 BTN3A1 (0.34) BTN3A1
SCHEMBL26332341 0.93 BTN3A1 (0.31) BTN3A1
SCHEMBL26337187 0.93 BTN3A1 (0.32) BTN3A1
SCHEMBL23819102 0.93 BTN3A1 (0.32) BTN3A1
SCHEMBL26332387 0.93 BTN3A1 (0.40) BTN3A1
SCHEMBL26333419 0.92 BTN3A1 (0.32) BTN3A1
SCHEMBL26333118 0.91 BTN3A1 (0.31) BTN3A1
SCHEMBL23818634 0.91 BTN3A1 (0.32) BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767337-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2023-09-26 — — US disclosed
US-20210284670-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284670-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885
US-11767337-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 BTN3A1 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback