SCHEMBL23822246

SCHEMBL23822246

N=C(/N=C(\N)c1cc(-c2ccccc2)cc2oc3ccccc3c12)c1ccc2ccccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.38
PLAU P00749 4/20 0.38
PLG P00747 3/20 0.38
PRSS1 P07477 3/20 0.38
KLKB1 P03952 1/20 0.38
KLK1 P06870 1/20 0.38
F12 P00748 1/20 0.36
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HTR2B P41595 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
CYP1A2 P05177 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 2/20 0.33
GLA P06280 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24657648 0.88 PRSS1 (0.43) F2PLAUPLGPRSS1MAPT
SCHEMBL24658033 0.88 F2 (0.42) F2PLAUPLGPRSS1KLKB1
SCHEMBL24655489 0.88 PLAU (0.36) F2PLAUPLGPRSS1KLKB1
SCHEMBL23822457 0.84 HTR2B (0.36) F2PLAUPLGPRSS1KLKB1
SCHEMBL23822492 0.83 PLAU (0.38) F2PLAUPLGPRSS1KLKB1
SCHEMBL25506602 0.83 HTR2B (0.36) F2PLAUPLGPRSS1MAPT
SCHEMBL23822273 0.83 HTR2B (0.36) F2PLAUPLGPRSS1KLKB1
SCHEMBL23283969 0.81 F2 (0.40) F2PLAUPLGPRSS1KLKB1
SCHEMBL25505739 0.81 PLAU (0.37) F2PLAUPLGPRSS1KLKB1
SCHEMBL25008980 0.81 WDR5 (0.40) PRSS1KLKB1GRIN2BALDH1A1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed
WO-2021230715-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2021-11-18 WO disclosed
WO-2021230714-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2021-11-18 WO disclosed
WO-2021182893-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2021-09-16 WO disclosed