Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311368 | 0.85 | HRH3 (0.36) | CHRM5CHRM3ALDH1A1CNR2POLB | |
| SCHEMBL19010253 | 0.80 | CHRM5 (0.40) | CHRM5CHRM3ALDH1A1CNR2POLB | |
| SCHEMBL26882750 | 0.79 | CACNA1H (0.48) | ALDH1A1LMNAGAA | |
| SCHEMBL13214851 | 0.75 | ALDH1A1 (0.46) | CHRM5CHRM3ALDH1A1POLB | |
| SCHEMBL14671225 | 0.73 | HSD17B10 (0.41) | ALDH1A1GAA | |
| SCHEMBL17176291 | 0.72 | PIK3R1 (0.38) | CHRM5CHRM3ALDH1A1POLBCYP2C19 | |
| SCHEMBL23962914 | 0.72 | SMN1; SMN2 (0.40) | LMNA | |
| SCHEMBL6039740 | 0.71 | — | — | |
| SCHEMBL6218142 | 0.71 | ALDH1A1 (0.59) | CHRM5CHRM3ALDH1A1POLBGAA | |
| SCHEMBL18743856 | 0.71 | ALDH1A1 (0.34) | CHRM5CHRM3ALDH1A1LMNAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180235-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | 四川海思科制药有限公司 | 2021-09-16 | — | — | WO | disclosed |