⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176701 | 0.98 | — | — | |
| SCHEMBL3080297 | 0.80 | FDPS (0.45) | — | |
| SCHEMBL3080934 | 0.80 | FDPS (0.45) | — | |
| SCHEMBL18191068 | 0.77 | — | — | |
| SCHEMBL20083635 | 0.76 | — | — | |
| SCHEMBL10680 | 0.74 | — | — | |
| SCHEMBL647572 | 0.72 | — | — | |
| Water SCHEMBL3086211 | 0.72 | TSHR (0.44) | — | |
| Bromide SCHEMBL714157 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL31520468 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2021180235-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | 四川海思科制药有限公司 | 2021-09-16 | — | — | WO | disclosed |