SCHEMBL23824979

SCHEMBL23824979

CCCCCCC(F)C(F)(F)C(O)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
FDPS P14324 4/20 0.40
LMNA P02545 1/20 0.40
FAAH O00519 7/20 0.36
CES1 P23141 5/20 0.36
GPR84 Q9NQS5 3/20 0.36
CES2 O00748 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23825006 1.00 MAPT (0.44) MAPTFDPSLMNAFAAHCES1
SCHEMBL3010559 0.98 MAPT (0.41) MAPTFDPSLMNAFAAHCES1
SCHEMBL2998995 0.91 FDPS (0.34) MAPTFDPSFAAHCES1CES2
SCHEMBL9444837 0.88 MAPT (0.41) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825142 0.88 MAPT (0.44) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825055 0.88 MAPT (0.44) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825039 0.88 MAPT (0.44) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825196 0.88 MAPT (0.44) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825146 0.86 MAPT (0.38) MAPTFDPSLMNAFAAHCES1
SCHEMBL23825044 0.85 MAPT (0.41) MAPTFDPSLMNAFAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882235-B1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND UNIV KOBE NAT UNIV CORP (JP) 2025-01-22 EP disclosed
US-12060312-B2 Production method for isocyanate compound NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2024-08-13 US disclosed
WO-2022065133-A1 METHOD FOR PRODUCING CARBONATE COMPOUND 国立大学法人神戸大学 2022-03-31 WO disclosed
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2022-01-06 US disclosed
EP-3882235-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND National University Corporation Kobe University (JP) 2021-09-22 EP disclosed
CN-113015719-A Method for producing isocyanate compound 国立大学法人神户大学 2021-06-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060312-B2 Production method for isocyanate compound IDH2, CBR3, IDH3A MAPT 1751/4885FDPS 216/4885LMNA 3593/4885
US-20220002234-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND IDH2, CBR3, IDH3A MAPT 1751/4885FDPS 216/4885LMNA 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.