SCHEMBL23826716

SCHEMBL23826716

CC(Nc1cc(C(=O)O)cc(F)c1C(F)(F)F)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 8/20 0.46
▸ DPP4 P27487 1/20 0.46
▸ MMP13 P45452 2/20 0.43
▸ STS P08842 1/20 0.43
▸ KMT2A Q03164 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ P2RY14 Q15391 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31336630 1.00 GPR119 (0.46) GPR119DPP4MMP13STSKMT2A
SCHEMBL23826712 1.00 GPR119 (0.46) GPR119DPP4MMP13STSKMT2A
SCHEMBL23826048 0.88 DPP4 (0.46) GPR119DPP4MMP13STSKMT2A
SCHEMBL23826051 0.88 DPP4 (0.46) GPR119DPP4MMP13STSKMT2A
SCHEMBL31336499 0.87 DPP4 (0.48) GPR119DPP4MMP13STSKMT2A
SCHEMBL23827019 0.87 DPP4 (0.48) GPR119DPP4MMP13STSKMT2A
SCHEMBL23826456 0.87 DPP4 (0.48) GPR119DPP4MMP13STSKMT2A
SCHEMBL23826863 0.87 STS (0.40) GPR119DPP4STSKMT2AMEN1
SCHEMBL23826314 0.87 STS (0.40) GPR119DPP4STSKMT2AMEN1
SCHEMBL23826013 0.87 GPR119 (0.45) GPR119DPP4MMP13STSKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220024921-A1 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL NIPPON SHINYAKU CO., LTD. (JP) 2022-01-27 — — US disclosed
EP-3882239-A1 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE Nippon Shinyaku Co., Ltd. (JP) 2021-09-22 — — EP disclosed
CN-113302184-A 1,3, 4-oxadiazolinone compounds and drugs 日本新药株式会社 2021-08-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024921-A1 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL PIM1, PIM3, PIM2 GPR119 3488/4885DPP4 32/4885MMP13 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback